This small setup can produce enough uranium fuel for 3,000 reactors. I also squeezed some reprocessing centrifuges in to deal with the spent fuel.
Thanks, ranzolger, for providing the reprocessing numbers. With this configuration, you will need a centrifuge for every 100 reactors. So, with two centrifuges, this blueprint can handle up to 200 reactors on the reprocessing side. Extend upwards as needed for additional reactors.