Run your base with the power of nuclear friendship!
For building on lakes (or anywhere with a water well mod). All water intakes are internally connected, allowing it to be run off a single offshore pump when placed on land. There are 4 designated water intake spots, one at each corner, near a substation.
Designed for continuous 800 MW load, and optimized for minimal bot activity and even fuel distribution. A chain of 10 power plants (netting continuous 8 GW) can be serviced by 8 logistic robots at maximum, non-infinite research.
Tiling
Tile along the long edge to get the tiling as shown in the top of the image. The power grids and logistic networks will then connect properly. The four outer substations are shared by two adjacent power plants.
Startup
In a power void, start the power plant with 1 uranium fuel cell per reactor. If outside power is present, simply provide fuel cells via the logistic network.
BP Version
v5.0 for Factorio 2.0
Screenhot note
The Screenshot is from Factorio 1.1 and still shows the previously-included radar and 8 offshore pumps. These components are no longer present in blueprint version 5.0.