Have you ever had a burning desire to wonder where all your U238 went? Do you ever find yourself short on U235? Does your OCD ever drive you crazy like it does me? Do you like pointlessly huge blueprinted refineries that take enormous amounts of resources and create more problems than it solves?
This is the setup for you!
This setup will take raw uranium ore and turn it into obscene amounts of U235, and as a bonus, make you wonder what you are doing with your life.
It features a balancer input for ore, a balancer input for U238/U235, refines all of it into U235, and outputs excess into another balancer/sorter/balancer to get 235 on one side of the belt and 238 on the other, and even recycles spent uranium fuel cells back into U238. It also can take resources mined from other types (copper, iron, etc) and dispose of them to the logistic network, so if you have uranium ore butted up against another resource, mine away, no problem.
It takes a bit of time to get going, but once it does, you will have no problems with keeping U235 coming, and U238, or the lack thereof, will be your new problem.