Just the Katherine of Sky kovarex setup but with some logic, it only use 40 u-235 to start the enrichment procces, then it pull outs 1 u-235 from Centrifuge to be used for the rest, It can be modify to work with 80 u-235 instead of 40 for more eficiency between cycles, just change the value on the filter inserter and in the Decider
Important Check V2 https://factorioprints.com/view/-LBxE7YG0O2-eNrd7Kx8