An updated version of Nytromance Games's plan, but actually functional: Correct underground pipe and belt lengths. Intended to allow one to begin with this tier of science, can be expanded if higher spm is desired. If you also use my E2 plan, you can build that next to E1 and route plasma, ion, and particle streams over to it, once you add more generation for them.
Factorio 2.0, Krastorio 2, Space Exploration 0.7x, stringweasel's Valves mod, and xkyouchoux's Space Age Building Integration mods. Should be easy to adjust without the last two.